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What is Spravato?

Spravato is a prescription nasal spray used to treat adults with treatment-resistant depression and major depressive disorder with suicidal thoughts or actions. It is administered in a medical setting under direct supervision, where patients are closely monitored throughout the entire treatment session for safety and comfort.

All About SPRAVATO

How It Works
 

Spravato works differently from traditional antidepressants. Instead of primarily targeting serotonin, it affects glutamate, a brain chemical involved in mood regulation and neural connections. This different pathway may help some patients experience relief when other medications have not been effective.

Who Qualifies

Spravato is typically considered for adults who have tried at least two antidepressant medications without sufficient improvement. Every patient must be evaluated by a qualified provider to determine if they are a good candidate. Certain conditions, such as uncontrolled high blood pressure or specific medical concerns, may prevent someone from receiving treatment.

 

What to Expect

Treatment begins with an initial consultation to review your history and determine eligibility. If appropriate, our team will help with insurance verification and prior authorization. Spravato is usually given twice per week at the start of treatment. Each session is done in-office, and patients are monitored for about two hours afterward. Because of its effects, you will need someone to drive you home after each visit.

 

Safety and Side Effects

Common side effects may include dizziness, dissociation, nausea, sedation, or mild increases in blood pressure. These effects are typically temporary and are monitored closely by clinical staff. Treatment is provided under a structured safety program that ensures patients are observed and supported during each visit.

Benefits

Some patients may experience improvement in symptoms within hours to days. Spravato offers an option for individuals who have not responded well to other treatments and may help reduce severe depressive symptoms, including suicidal thoughts, more quickly than standard antidepressants in some cases.

 

Cost and Insurance

Many insurance plans cover Spravato with prior authorization. Our office assists patients with insurance verification and approval steps. Self-pay options may be available depending on individual circumstances.

Frequently asked questions

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Disclaimer

Huckleberry Health, LLC is not an emergency or crisis service. If you are experiencing a medical or mental health emergency, please call 911, go to the nearest emergency room or reach out to the Suicide & Crisis Lifeline by dialing 988 for immediate assistance.

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